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BMCBI
2004
208views more  BMCBI 2004»
14 years 9 months ago
Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures
Background: Hidden Markov Models (HMMs) have proven very useful in computational biology for such applications as sequence pattern matching, gene-finding, and structure prediction...
Vadim Alexandrov, Mark Gerstein
IMC
2010
ACM
14 years 7 months ago
Primitives for active internet topology mapping: toward high-frequency characterization
Current large-scale topology mapping systems require multiple days to characterize the Internet due to the large amount of probing traffic they incur. The accuracy of maps from ex...
Robert Beverly, Arthur Berger, Geoffrey G. Xie
ML
2006
ACM
143views Machine Learning» more  ML 2006»
14 years 9 months ago
Mathematical applications of inductive logic programming
The application of Inductive Logic Programming to scientific datasets has been highly successful. Such applications have led to breakthroughs in the domain of interest and have dri...
Simon Colton, Stephen Muggleton
BMCBI
2011
14 years 4 months ago
Phenotype Recognition with Combined Features and Random Subspace Classifier Ensemble
Background: Automated, image based high-content screening is a fundamental tool for discovery in biological science. Modern robotic fluorescence microscopes are able to capture th...
Bailing Zhang, Tuan D. Pham
BMCBI
2004
112views more  BMCBI 2004»
14 years 9 months ago
A double classification tree search algorithm for index SNP selection
Background: In population-based studies, it is generally recognized that single nucleotide polymorphism (SNP) markers are not independent. Rather, they are carried by haplotypes, ...
Peisen Zhang, Huitao Sheng, Ryuhei Uehara