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» Computing persistent homology
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BIBE
2006
IEEE
119views Bioinformatics» more  BIBE 2006»
15 years 3 months ago
Large Grain Size Stochastic Optimization Alignment
DNA sequence alignment is a critical step in identifying homology between organisms. The most widely used alignment program, ClustalW, is known to suffer from the local minima pro...
Perry Ridge, Hyrum Carroll, Dan Sneddon, Mark J. C...
GCB
2003
Springer
105views Biometrics» more  GCB 2003»
15 years 3 months ago
In silico prediction of UTR repeats using clustered EST data
Clustering of EST data is a method for the non-redundant representation of an organisms transcriptome. During clustering of large amounts of EST data, usually some large clusters ...
Stefan A. Rensing, Daniel Lang, Ralf Reski
RECOMB
1999
Springer
15 years 2 months ago
Classifying proteins by family using the product of correlated p-values
An important goal in bioinformatics is determining the homology and function of proteins from their sequences. Pairwise sequence similarity algorithms are often employed for this ...
Timothy L. Bailey, William Noble Grundy
CIBCB
2006
IEEE
15 years 1 months ago
Efficient Probe Selection in Microarray Design
Abstract-- The DNA microarray technology, originally developed to measure the level of gene expression, had become one of the most widely used tools in genomic study. Microarrays h...
Leszek Gasieniec, Cindy Y. Li, Paul Sant, Prudence...
BMCBI
2010
112views more  BMCBI 2010»
14 years 10 months ago
Orientation-dependent backbone-only residue pair scoring functions for fixed backbone protein design
Background: Empirical scoring functions have proven useful in protein structure modeling. Most such scoring functions depend on protein side chain conformations. However, backbone...
Andrew J. Bordner