For transmembrane proteins experimental determina-tion of three-dimensional structure is problematic. However, membrane proteins have important impact for molecular biology in gen...
eraction networks. In this abstract, we extend this approach by mining functional flow patterns for the purpose of detecting small-sized modules for specific functions. Methods Our...
Background: Biological processes are mediated by networks of interacting genes and proteins. Efforts to map and understand these networks are resulting in the proliferation of int...
Svetlana Pacifico, Guozhen Liu, Stephen Guest, Jod...
Protein interactions and complexes are major components of biological systems. Recent genome-wide applications of tandem affinity purification (TAP) in yeast have increased signifi...
An important goal in bioinformatics is determining the homology and function of proteins from their sequences. Pairwise sequence similarity algorithms are often employed for this ...