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» Computing with Evolving Proteins
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ISMB
1996
14 years 11 months ago
Refining Neural Network Predictions for Helical Transmembrane Proteins by Dynamic Programming
For transmembrane proteins experimental determina-tion of three-dimensional structure is problematic. However, membrane proteins have important impact for molecular biology in gen...
Burkhard Rost, Rita Casadio, Piero Fariselli
BMCBI
2008
123views more  BMCBI 2008»
14 years 10 months ago
Functional module detection by functional flow pattern mining in protein interaction networks
eraction networks. In this abstract, we extend this approach by mining functional flow patterns for the purpose of detecting small-sized modules for specific functions. Methods Our...
Young-Rae Cho, Lei Shi, Aidong Zhang
BMCBI
2006
182views more  BMCBI 2006»
14 years 10 months ago
A database and tool, IM Browser, for exploring and integrating emerging gene and protein interaction data for Drosophila
Background: Biological processes are mediated by networks of interacting genes and proteins. Efforts to map and understand these networks are resulting in the proliferation of int...
Svetlana Pacifico, Guozhen Liu, Stephen Guest, Jod...
RECOMB
2008
Springer
15 years 10 months ago
Bootstrapping the Interactome: Unsupervised Identification of Protein Complexes in Yeast
Protein interactions and complexes are major components of biological systems. Recent genome-wide applications of tandem affinity purification (TAP) in yeast have increased signifi...
Caroline C. Friedel, Jan Krumsiek, Ralf Zimmer
70
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RECOMB
1999
Springer
15 years 2 months ago
Classifying proteins by family using the product of correlated p-values
An important goal in bioinformatics is determining the homology and function of proteins from their sequences. Pairwise sequence similarity algorithms are often employed for this ...
Timothy L. Bailey, William Noble Grundy