Algorithmsbasedonprobability theorycanaddressissues of uncertainty directly throughtheir representational frameworkandtheir theoryfor data combination.In this paper, wediscuss the...
One of the major goals of computational sequence analysis is to find sequence similarities, which could serve as evidence of structural and functional conservation, as well as of ...
Background: In biological sequence analysis, position specific scoring matrices (PSSMs) are widely used to represent sequence motifs in nucleotide as well as amino acid sequences....
Michael Beckstette, Robert Homann, Robert Giegeric...
The task of finding saddle points on potential energy surfaces plays a crucial role in understanding the dynamics of a micromolecule as well as in studying the folding pathways of...
: The major bottleneck of today's atomistic molecular dynamics (MD) simulations is that because of the enormous computational effort involved, only processes at nanoseconds to...