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» Constraint Based Methods for Biological Sequence Analysis
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108
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ISMB
2004
15 years 1 months ago
Predicting gene regulation by sigma factors in Bacillus subtilis from genome-wide data
Motivation: Sigma factors regulate the expression of genes in Bacillus subtilis at the transcriptional level. First we assess the ability of currently available gene regulatory ne...
Michiel J. L. de Hoon, Yuko Makita, Seiya Imoto, K...
ALMOB
2006
155views more  ALMOB 2006»
15 years 19 days ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg
85
Voted
CIBCB
2006
IEEE
15 years 6 months ago
Machine Learning in Basecalling Decoding Trace Peak Behaviour
— DNA sequence basecalling is commonly regarded as a solved problem, despite significant error rates being reflected in inaccuracies in databases and genome annotations. These er...
David Thornley, Stavros Petridis
BICOB
2010
Springer
14 years 10 months ago
Multiple Kernel Learning for Fold Recognition
Fold recognition is a key problem in computational biology that involves classifying protein sharing structural similarities into classes commonly known as "folds". Rece...
Huzefa Rangwala
BMCBI
2005
107views more  BMCBI 2005»
15 years 14 days ago
ProbeMaker: an extensible framework for design of sets of oligonucleotide probes
Background: Procedures for genetic analyses based on oligonucleotide probes are powerful tools that can allow highly parallel investigations of genetic material. Such procedures r...
Johan Stenberg, Mats Nilsson, Ulf Landegren