Background: Boolean network (BN) modeling is a commonly used method for constructing gene regulatory networks from time series microarray data. However, its major drawback is that...
It is widely accepted that the optimal alignment between a pair of proteins or nucleic acid sequences that minimizes the edit distance may not necessarily re
ect the correct biolog...
Everybody agrees that curing DFM/DFY issues is of paramount importance at 65 nanometers and beyond. Unfortunately, there is disagreement about how and when to cure them. “Surgeo...
Marco Casale-Rossi, Andrzej J. Strojwas, Robert C....
Background: The identification and characterization of interacting domain pairs is an important step towards understanding protein interactions. In the last few years, several met...
Background: In order to compute pattern statistics in computational biology a Markov model is commonly used to take into account the sequence composition. Usually its parameter mu...