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» Counting Independent Sets Using the Bethe Approximation
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BMCBI
2007
197views more  BMCBI 2007»
14 years 12 months ago
Boolean networks using the chi-square test for inferring large-scale gene regulatory networks
Background: Boolean network (BN) modeling is a commonly used method for constructing gene regulatory networks from time series microarray data. However, its major drawback is that...
Haseong Kim, Jae K. Lee, Taesung Park
CPM
1993
Springer
154views Combinatorics» more  CPM 1993»
15 years 4 months ago
On Suboptimal Alignments of Biological Sequences
It is widely accepted that the optimal alignment between a pair of proteins or nucleic acid sequences that minimizes the edit distance may not necessarily re ect the correct biolog...
Dalit Naor, Douglas L. Brutlag
DATE
2007
IEEE
146views Hardware» more  DATE 2007»
15 years 6 months ago
DFM/DFY: should you trust the surgeon or the family doctor?
Everybody agrees that curing DFM/DFY issues is of paramount importance at 65 nanometers and beyond. Unfortunately, there is disagreement about how and when to cure them. “Surgeo...
Marco Casale-Rossi, Andrzej J. Strojwas, Robert C....
BMCBI
2008
97views more  BMCBI 2008»
14 years 12 months ago
Interrogating domain-domain interactions with parsimony based approaches
Background: The identification and characterization of interacting domain pairs is an important step towards understanding protein interactions. In the last few years, several met...
Katia S. Guimarães, Teresa M. Przytycka
ALMOB
2006
80views more  ALMOB 2006»
14 years 12 months ago
Pattern statistics on Markov chains and sensitivity to parameter estimation
Background: In order to compute pattern statistics in computational biology a Markov model is commonly used to take into account the sequence composition. Usually its parameter mu...
Grégory Nuel