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COOTS
1996
14 years 11 months ago
The Any Framework: A Pragmatic Approach to Flexibility
During the development of Beyond-Sniff, a distributed multi-user development platform, we were confronted with various, apparently unrelated problems: data, control, and user inte...
Kai-Uwe Mätzel, Walter R. Bischofberger
VLDB
2007
ACM
198views Database» more  VLDB 2007»
15 years 10 months ago
The End of an Architectural Era (It's Time for a Complete Rewrite)
In previous papers [SC05, SBC+07], some of us predicted the end of "one size fits all" as a commercial relational DBMS paradigm. These papers presented reasons and exper...
Michael Stonebraker, Samuel Madden, Daniel J. Abad...
SIGMOD
1997
ACM
160views Database» more  SIGMOD 1997»
15 years 2 months ago
Improved Query Performance with Variant Indexes
: The read-mostly environment of data warehousing makes it possible to use more complex indexes to speed up queries than in situations where concurrent updatesare present. The curr...
Patrick E. O'Neil, Dallan Quass
BMCBI
2008
96views more  BMCBI 2008»
14 years 10 months ago
Mapping proteins to disease terminologies: from UniProt to MeSH
Background: Although the UniProt KnowledgeBase is not a medical-oriented database, it contains information on more than 2,000 human proteins involved in pathologies. However, thes...
Anaïs Mottaz, Yum Lina Yip, Patrick Ruch, Ann...
JIB
2006
106views more  JIB 2006»
14 years 10 months ago
A structural keystone for drug design
3D-structures of proteins and potential ligands are the cornerstones of rational drug design. The first brick to build upon is selecting a protein target and finding out whether b...
Kristian Rother, Mathias Dunkel, Elke Michalsky, S...