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BMCBI
2010
155views more  BMCBI 2010»
14 years 9 months ago
A flexible R package for nonnegative matrix factorization
Background: Nonnegative Matrix Factorization (NMF) is an unsupervised learning technique that has been applied successfully in several fields, including signal processing, face re...
Renaud Gaujoux, Cathal Seoighe
BMCBI
2007
147views more  BMCBI 2007»
14 years 9 months ago
MaxAlign: maximizing usable data in an alignment
Background: The presence of gaps in an alignment of nucleotide or protein sequences is often an inconvenience for bioinformatical studies. In phylogenetic and other analyses, for ...
Rodrigo Gouveia-Oliveira, Peter Wad Sackett, Ander...
BMCBI
2007
124views more  BMCBI 2007»
14 years 9 months ago
A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality
Background: Identifying all protein complexes in an organism is a major goal of systems biology. In the past 18 months, the results of two genome-scale tandem affinity purificatio...
G. Traver Hart, Insuk Lee, Edward M. Marcotte
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BMCBI
2008
101views more  BMCBI 2008»
14 years 9 months ago
Reranking candidate gene models with cross-species comparison for improved gene prediction
Background: Most gene finders score candidate gene models with state-based methods, typically HMMs, by combining local properties (coding potential, splice donor and acceptor patt...
Qian Liu, Koby Crammer, Fernando C. N. Pereira, Da...
BMCBI
2006
202views more  BMCBI 2006»
14 years 9 months ago
Spectral embedding finds meaningful (relevant) structure in image and microarray data
Background: Accurate methods for extraction of meaningful patterns in high dimensional data have become increasingly important with the recent generation of data types containing ...
Brandon W. Higgs, Jennifer W. Weller, Jeffrey L. S...