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BMCBI
2006
205views more  BMCBI 2006»
14 years 9 months ago
Application of Petri net based analysis techniques to signal transduction pathways
Background: Signal transduction pathways are usually modelled using classical quantitative methods, which are based on ordinary differential equations (ODEs). However, some diffic...
Andrea Sackmann, Monika Heiner, Ina Koch
BMCBI
2006
167views more  BMCBI 2006»
14 years 9 months ago
The bovine QTL viewer: a web accessible database of bovine Quantitative Trait Loci
Background: Many important agricultural traits such as weight gain, milk fat content and intramuscular fat (marbling) in cattle are quantitative traits. Most of the information on...
Pavana Polineni, Prathyusha Aragonda, Suresh R. Xa...
BMCBI
2006
85views more  BMCBI 2006»
14 years 9 months ago
Searching for interpretable rules for disease mutations: a simulated annealing bump hunting strategy
Background: Understanding how amino acid substitutions affect protein functions is critical for the study of proteins and their implications in diseases. Although methods have bee...
Rui Jiang, Hua Yang, Fengzhu Sun, Ting Chen
BMCBI
2006
173views more  BMCBI 2006»
14 years 9 months ago
Kernel-based distance metric learning for microarray data classification
Background: The most fundamental task using gene expression data in clinical oncology is to classify tissue samples according to their gene expression levels. Compared with tradit...
Huilin Xiong, Xue-wen Chen
BMCBI
2006
111views more  BMCBI 2006»
14 years 9 months ago
Tools for integrated sequence-structure analysis with UCSF Chimera
Background: Comparing related structures and viewing the structures in the context of sequence alignments are important tasks in protein structure-function research. While many pr...
Elaine C. Meng, Eric F. Pettersen, Gregory S. Couc...
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