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122
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BMCBI
2006
15 years 14 days ago
2006
Background: DNA copy number alterations are one of the main characteristics of the cancer cell karyotype and can contribute to the complex phenotype of these cells. These alterati...
114
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BMCBI
2006
15 years 14 days ago
2006
Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
111
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BMCBI
2005
15 years 10 days ago
2005
Background: The large gap between the number of protein sequences in databases and the number of functionally characterized proteins calls for the development of a fast computatio...
90
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BMCBI
2006
15 years 14 days ago
2006
Background: Biological databases and pathway knowledgebases are proliferating rapidly. We are developing software tools for computer-aided hypothesis design and evaluation, and we...
119
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BMCBI
2006
15 years 14 days ago
2006
Background: The emerging field of integrative bioinformatics provides the tools to organize and systematically analyze vast amounts of highly diverse biological data and thus allo...