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BMCBI
2008
140views more  BMCBI 2008»
14 years 10 months ago
Improved accuracy of multiple ncRNA alignment by incorporating structural information into a MAFFT-based framework
Background: Structural alignment of RNAs is becoming important, since the discovery of functional non-coding RNAs (ncRNAs). Recent studies, mainly based on various approximations ...
Kazutaka Katoh, Hiroyuki Toh
BMCBI
2008
142views more  BMCBI 2008»
14 years 10 months ago
Identification of biomarkers for genotyping Aspergilli using non-linear methods for clustering and classification
Background: In the present investigation, we have used an exhaustive metabolite profiling approach to search for biomarkers in recombinant Aspergillus nidulans (mutants that produ...
Irene Kouskoumvekaki, Zhiyong Yang, Svava Ó...
BMCBI
2007
125views more  BMCBI 2007»
14 years 10 months ago
Statistical tests to compare motif count exceptionalities
Background: Finding over- or under-represented motifs in biological sequences is now a common task in genomics. Thanks to p-value calculation for motif counts, exceptional motifs ...
Stéphane Robin, Sophie Schbath, Vincent Van...
BMCBI
2006
100views more  BMCBI 2006»
14 years 9 months ago
DNPTrapper: an assembly editing tool for finishing and analysis of complex repeat regions
Background: Many genome projects are left unfinished due to complex, repeated regions. Finishing is the most time consuming step in sequencing and current finishing tools are not ...
Erik Arner, Martti T. Tammi, Anh-Nhi Tran, Ellen K...
BMCBI
2006
123views more  BMCBI 2006»
14 years 9 months ago
An Automated Method for Rapid Identification of Putative Gene Family Members in Plants
Background: Gene duplication events have played a significant role in genome evolution, particularly in plants. Exhaustive searches for all members of a known gene family as well ...
Ronald L. Frank, Ajay Mane, Fikret Erçal