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» Dynamic simulation of regulatory networks using SQUAD
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BMCBI
2010
152views more  BMCBI 2010»
14 years 11 months ago
Comparative study of discretization methods of microarray data for inferring transcriptional regulatory networks
Background: Microarray data discretization is a basic preprocess for many algorithms of gene regulatory network inference. Some common discretization methods in informatics are us...
Yong Li, Lili Liu, Xi Bai, Hua Cai, Wei Ji, Dianji...
BIOINFORMATICS
2011
14 years 6 months ago
Inverse perturbation for optimal intervention in gene regulatory networks
Motivation: Analysis and intervention in the dynamics of gene regulatory networks is at the heart of emerging efforts in the development of modern treatment of numerous ailments i...
Nidhal Bouaynaya, Roman Shterenberg, Dan Schonfeld
EVOW
2007
Springer
15 years 5 months ago
Bio-mimetic Evolutionary Reverse Engineering of Genetic Regulatory Networks
The effective reverse engineering of biochemical networks is one of the great challenges of systems biology. The contribution of this paper is two-fold: 1) We introduce a new meth...
Daniel Marbach, Claudio Mattiussi, Dario Floreano
TACAS
2007
Springer
92views Algorithms» more  TACAS 2007»
15 years 5 months ago
Model Checking Liveness Properties of Genetic Regulatory Networks
Abstract. Recent studies have demonstrated the possibility to build genetic regulatory networks that confer a desired behavior to a living organism. However, the design of these ne...
Grégory Batt, Calin Belta, Ron Weiss
CIBCB
2005
IEEE
15 years 5 months ago
Feedback Memetic Algorithms for Modeling Gene Regulatory Networks
— In this paper we address the problem of finding gene regulatory networks from experimental DNA microarray data. We focus on the evaluation of the performance of memetic algori...
Christian Spieth, Felix Streichert, Jochen Supper,...