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ALMOB
2006
155views more  ALMOB 2006»
15 years 27 days ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg
131
Voted
BMCBI
2007
136views more  BMCBI 2007»
15 years 26 days ago
Prediction of tissue-specific cis-regulatory modules using Bayesian networks and regression trees
Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...
Xiaoyu Chen, Mathieu Blanchette
131
Voted
BMCBI
2010
110views more  BMCBI 2010»
14 years 11 months ago
Improvements to previous algorithms to predict gene structure and isoform concentrations using Affymetrix Exon arrays
Background: Exon arrays provide a way to measure the expression of different isoforms of genes in an organism. Most of the procedures to deal with these arrays are focused on gene...
Miguel A. Anton, Ander Aramburu, Angel Rubio
132
Voted
BMCBI
2010
123views more  BMCBI 2010»
14 years 7 months ago
Predicting conserved protein motifs with Sub-HMMs
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...
Kevin Horan, Christian R. Shelton, Thomas Girke
137
Voted
CDC
2010
IEEE
160views Control Systems» more  CDC 2010»
14 years 7 months ago
Model-on-Demand predictive control for nonlinear hybrid systems with application to adaptive behavioral interventions
This paper presents a data-centric modeling and predictive control approach for nonlinear hybrid systems. System identification of hybrid systems represents a challenging problem b...
Naresh N. Nandola, Daniel E. Rivera