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BMCBI
2008
108views more  BMCBI 2008»
14 years 11 months ago
New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic backgroun
Background: Few genetic factors predisposing to the sporadic form of amyotrophic lateral sclerosis (ALS) have been identified, but the pathology itself seems to be a true multifac...
Silvana Penco, Massimo Buscema, Maria Cristina Pat...
120
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BMCBI
2006
156views more  BMCBI 2006»
14 years 11 months ago
Score-based prediction of genomic islands in prokaryotic genomes using hidden Markov models
Background: Horizontal gene transfer (HGT) is considered a strong evolutionary force shaping the content of microbial genomes in a substantial manner. It is the difference in spee...
Stephan Waack, Oliver Keller, Roman Asper, Thomas ...
BMCBI
2006
103views more  BMCBI 2006»
14 years 11 months ago
Meta-All: a system for managing metabolic pathway information
Background: Many attempts are being made to understand biological subjects at a systems level. A major resource for these approaches are biological databases, storing manifold inf...
Stephan Weise, Ivo Grosse, Christian Klukas, Dirk ...
88
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BMCBI
2007
126views more  BMCBI 2007»
14 years 11 months ago
Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation
Background: Biochemical investigations over the last decades have elucidated an increasingly complete image of the cellular metabolism. To derive a systems view for the regulation...
Gunnar Schramm, Marc Zapatka, Roland Eils, Rainer ...
94
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JSAC
2008
111views more  JSAC 2008»
14 years 11 months ago
Socially-aware routing for publish-subscribe in delay-tolerant mobile ad hoc networks
Abstract--Applications involving the dissemination of information directly relevant to humans (e.g., service advertising, news spreading, environmental alerts) often rely on publis...
Paolo Costa, Cecilia Mascolo, Mirco Musolesi, Gian...