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BMCBI
2005
93views more  BMCBI 2005»
14 years 9 months ago
Two-part permutation tests for DNA methylation and microarray data
Background: One important application of microarray experiments is to identify differentially expressed genes. Often, small and negative expression levels were clipped-off to be e...
Markus Neuhäuser, Tanja Boes, Karl-Heinz J&ou...
BMCBI
2010
155views more  BMCBI 2010»
14 years 9 months ago
A flexible R package for nonnegative matrix factorization
Background: Nonnegative Matrix Factorization (NMF) is an unsupervised learning technique that has been applied successfully in several fields, including signal processing, face re...
Renaud Gaujoux, Cathal Seoighe
KDD
2004
ACM
314views Data Mining» more  KDD 2004»
15 years 10 months ago
Assessment of discretization techniques for relevant pattern discovery from gene expression data
In the domain of gene expression data analysis, various researchers have recently emphasized the promising application of pattern discovery techniques like association rule mining...
Ruggero G. Pensa, Claire Leschi, Jéré...
BMCBI
2010
105views more  BMCBI 2010»
14 years 9 months ago
Evaluation of fecal mRNA reproducibility via a marginal transformed mixture modeling approach
Background: Developing and evaluating new technology that enables researchers to recover gene-expression levels of colonic cells from fecal samples could be key to a non-invasive ...
Nysia I. George, Joanne R. Lupton, Nancy D. Turner...
BMCBI
2007
146views more  BMCBI 2007»
14 years 9 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...