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» Evolution of Biological Complexity
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114
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ICCS
2001
Springer
15 years 5 months ago
High-Performance Algorithm Engineering for Computational Phylogenetics
Abstract. Phylogeny reconstruction from molecular data poses complex optimization problems: almost all optimization models are NP-hard and thus computationally intractable. Yet app...
Bernard M. E. Moret, David A. Bader, Tandy Warnow
109
Voted
CBMS
2001
IEEE
15 years 4 months ago
An Interoperable Data Architecture for Data Exchange in a Biomedical Research Network
Knowledge discovery and data correlation require a unified approach to basic data management. However, achieving such an approach is nearly impossible with hundreds of disparate d...
Daniel J. Crichton, J. Steven Hughes, Gregory J. D...
99
Voted
IADIS
2008
15 years 2 months ago
Sisa: Seeded Iterative Signature Algorithm for Biclustering Gene Expression Data
One approach to reduce the complexity of the task in the analysis of large scale genome-wide expression is to group the genes showing similar expression patterns into what are cal...
Neelima Gupta, Seema Aggarwal
84
Voted
CEC
2010
IEEE
15 years 1 months ago
Evolutionary layered hypernetworks for identifying microRNA-mRNA regulatory modules
Abstract-- Exploring microRNA (miRNA) and mRNA regulatory interactions may give new insights into diverse biological phenomena. While elucidating complex miRNA-mRNA interactions ha...
Soo-Jin Kim, JungWoo Ha, Bado Lee, Byoung-Tak Zhan...
117
Voted
HPDC
2010
IEEE
15 years 1 months ago
Biocompute: towards a collaborative workspace for data intensive bio-science
The explosion of data in the biological community demands the development of more scalable and flexible portals for bioinformatic computation. To address this need, we put forth c...
Rory Carmichael, Patrick Braga-Henebry, Douglas Th...