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» Evolutionary sequence analysis of complete eukaryote genomes
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ALMOB
2006
155views more  ALMOB 2006»
14 years 10 months ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg
BMCBI
2007
87views more  BMCBI 2007»
14 years 9 months ago
A manually curated database of tetrapod mitochondrially encoded tRNA sequences and secondary structures
Background: Mitochondrial tRNAs have been the subject of study for structural biologists interested in their secondary structure characteristics, evolutionary biologists have rese...
Konstantin Yu Popadin, Leila A. Mamirova, Fyodor A...
BMCBI
2005
89views more  BMCBI 2005»
14 years 9 months ago
Comparative analysis of chromatin landscape in regulatory regions of human housekeeping and tissue specific genes
Background: Global regulatory mechanisms involving chromatin assembly and remodelling in the promoter regions of genes is implicated in eukaryotic transcription control especially...
Mythily Ganapathi, Pragya Srivastava, Sushanta Kum...
BMCBI
2004
174views more  BMCBI 2004»
14 years 9 months ago
SeeGH - A software tool for visualization of whole genome array comparative genomic hybridization data
Background: Array comparative genomic hybridization (CGH) is a technique which detects copy number differences in DNA segments. Complete sequencing of the human genome and the dev...
Bryan Chi, Ronald J. deLeeuw, Bradley P. Coe, Calu...
JIB
2007
89views more  JIB 2007»
14 years 9 months ago
A Methodology for Comparative Functional Genomics
The continuing and rapid increase in the number of fully sequenced genomes is creating new opportunities for comparative studies. However, although many genomic databases store da...
Intikhab Alam, Mike Cornell, Darren M. Soanes, Cor...