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BMCBI
2007
113views more  BMCBI 2007»
15 years 5 months ago
Learning biophysically-motivated parameters for alpha helix prediction
Background: Our goal is to develop a state-of-the-art protein secondary structure predictor, with an intuitive and biophysically-motivated energy model. We treat structure predict...
Blaise Gassend, Charles W. O'Donnell, William Thie...
ISCI
2008
124views more  ISCI 2008»
15 years 4 months ago
A weighted rough set based method developed for class imbalance learning
In this paper, we introduce weights into Pawlak rough set model to balance the class distribution of a data set and develop a weighted rough set based method to deal with the clas...
Jinfu Liu, Qinghua Hu, Daren Yu
IJDMB
2007
110views more  IJDMB 2007»
15 years 4 months ago
Transductive learning with EM algorithm to classify proteins based on phylogenetic profiles
: Phylogenetic profiles of proteins  strings of ones and zeros encoding respectively the presence and absence of proteins in a group of genomes  have recently been used to id...
Roger A. Craig, Li Liao
158
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TCBB
2008
120views more  TCBB 2008»
15 years 4 months ago
Learning Scoring Schemes for Sequence Alignment from Partial Examples
When aligning biological sequences, the choice of scoring scheme is critical. Even small changes in gap penalties, for example, can yield radically different alignments. A rigorous...
Eagu Kim, John D. Kececioglu
JMLR
2002
90views more  JMLR 2002»
15 years 4 months ago
Machine Learning with Data Dependent Hypothesis Classes
We extend the VC theory of statistical learning to data dependent spaces of classifiers. This theory can be viewed as a decomposition of classifier design into two components; the...
Adam Cannon, J. Mark Ettinger, Don R. Hush, Clint ...