We consider optimization problems that can be formulated as minimizing the cost of a feasible solution wT x over an arbitrary combinatorial feasible set F {0, 1}n . For these pro...
Background: Discovering approximately repeated patterns, or motifs, in biological sequences is an important and widely-studied problem in computational molecular biology. Most fre...
We describe a simple iterative method for proving a variety of results in combinatorial optimization. It is inspired by Jain’s iterative rounding method (FOCS 1998) for designing...
Given a set of taxa S and a complete set of quartet topologies Q over S, the problem of determining a phylogeny that satisfies the maximum number of topologies is called the Maxi...
A central problem in bioinformatics and systems biology is the selection of appropriate models in a rational and systematic way. This fundamentally combinatorial problem can be re...
Eric Yang, Timothy Maguire, Martin L. Yarmush, Ioa...