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» Extraction of informative genes from microarray data
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BMCBI
2010
108views more  BMCBI 2010»
15 years 3 months ago
Error, reproducibility and sensitivity : a pipeline for data processing of Agilent oligonucleotide expression arrays
Background: Expression microarrays are increasingly used to obtain large scale transcriptomic information on a wide range of biological samples. Nevertheless, there is still much ...
Benjamin Chain, Helen Bowen, John Hammond, Wilfrie...
BMCBI
2010
96views more  BMCBI 2010»
15 years 3 months ago
QTLminer: identifying genes regulating quantitative traits
Background: Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to...
Rudi Alberts, Klaus Schughart
BMCBI
2007
157views more  BMCBI 2007»
15 years 3 months ago
Constructing gene co-expression networks and predicting functions of unknown genes by random matrix theory
Background: Large-scale sequencing of entire genomes has ushered in a new age in biology. One of the next grand challenges is to dissect the cellular networks consisting of many i...
Feng Luo, Yunfeng Yang, Jianxin Zhong, Haichun Gao...
123
Voted
BIBM
2007
IEEE
137views Bioinformatics» more  BIBM 2007»
15 years 9 months ago
A Multi-metric Similarity Based Analysis of Microarray Data
Clustering has been shown to be effective in analyzing functional relationships of genes. However, no single clustering method with single distance metric is capable of capturing ...
Fatih Altiparmak, Selnur Erdal, Ozgur Ozturk, Haka...
JCB
2002
160views more  JCB 2002»
15 years 3 months ago
Inference from Clustering with Application to Gene-Expression Microarrays
There are many algorithms to cluster sample data points based on nearness or a similarity measure. Often the implication is that points in different clusters come from different u...
Edward R. Dougherty, Junior Barrera, Marcel Brun, ...