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BMCBI
2004
101views more  BMCBI 2004»
14 years 11 months ago
A database for G proteins and their interaction with GPCRs
Background: G protein-coupled receptors (GPCRs) transduce signals from extracellular space into the cell, through their interaction with G proteins, which act as switches forming ...
Antigoni L. Elefsinioti, Pantelis G. Bagos, Ioanni...
WABI
2001
Springer
142views Bioinformatics» more  WABI 2001»
15 years 4 months ago
Pattern Matching and Pattern Discovery Algorithms for Protein Topologies
We describe algorithms for pattern matching and pattern learning in TOPS diagrams (formal descriptions of protein topologies). These problems can be reduced to checking for subgrap...
Juris Viksna, David Gilbert
BIBE
2005
IEEE
126views Bioinformatics» more  BIBE 2005»
15 years 5 months ago
Suboptimal Alignments Improve the Detection of Weak Homologs in Sequence Database Searches
PSI-BLAST remains one of the popular tools for searching remote homologs in sequence databases. We recently demonstrated that hybrid alignment can function as the alignment core f...
Yuheng Li, Mario Lauria, Ralf Bundschuh
BMCBI
2007
148views more  BMCBI 2007»
14 years 11 months ago
fREDUCE: Detection of degenerate regulatory elements using correlation with expression
Background: The precision of transcriptional regulation is made possible by the specificity of physical interactions between transcription factors and their cognate binding sites ...
Randy Z. Wu, Christina Chaivorapol, Jiashun Zheng,...
BMCBI
2008
120views more  BMCBI 2008»
14 years 12 months ago
DBMLoc: a Database of proteins with multiple subcellular localizations
Background: Subcellular localization information is one of the key features to protein function research. Locating to a specific subcellular compartment is essential for a protein...
Song Zhang, Xuefeng Xia, Jincheng Shen, Yun Zhou, ...