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» Finding Gapped Motifs by a Novel Evolutionary Algorithm
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TCBB
2008
103views more  TCBB 2008»
14 years 9 months ago
DNA Motif Representation with Nucleotide Dependency
The problem of discovering novel motifs of binding sites is important to the understanding of gene regulatory networks. Motifs are generally represented by matrices (PWM or PSSM) o...
Francis Y. L. Chin, Henry C. M. Leung
CEC
2007
IEEE
15 years 3 months ago
An efficient Genetic Algorithm with uniform crossover for the multi-objective Airport Gate Assignment Problem
—Genetic Algorithms (GAs) have a good potential of solving the Gate Assignment Problem (GAP) at airport terminals, and the design of feasible and efficient evolutionary operators...
Xiao-Bing Hu, Ezequiel A. Di Paolo
BMCBI
2006
161views more  BMCBI 2006»
14 years 9 months ago
A novel approach to phylogenetic tree construction using stochastic optimization and clustering
Background: The problem of inferring the evolutionary history and constructing the phylogenetic tree with high performance has become one of the major problems in computational bi...
Ling Qin, Yixin Chen, Yi Pan, Ling Chen
127
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BMCBI
2005
201views more  BMCBI 2005»
14 years 9 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota
ALMOB
2006
155views more  ALMOB 2006»
14 years 9 months ago
Refining motifs by improving information content scores using neighborhood profile search
The main goal of the motif finding problem is to detect novel, over-represented unknown signals in a set of sequences (e.g. transcription factor binding sites in a genome). The mo...
Chandan K. Reddy, Yao-Chung Weng, Hsiao-Dong Chian...