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BMCBI
2007
134views more  BMCBI 2007»
15 years 2 months ago
Nearest Neighbor Networks: clustering expression data based on gene neighborhoods
Background: The availability of microarrays measuring thousands of genes simultaneously across hundreds of biological conditions represents an opportunity to understand both indiv...
Curtis Huttenhower, Avi I. Flamholz, Jessica N. La...
BMCBI
2008
115views more  BMCBI 2008»
15 years 2 months ago
Probe signal correction for differential methylation hybridization experiments
Background: Non-biological signal (or noise) has been the bane of microarray analysis. Hybridization effects related to probe-sequence composition and DNA dye-probe interactions h...
Dustin P. Potter, Pearlly Yan, Tim Hui-Ming Huang,...
BMCBI
2006
94views more  BMCBI 2006»
15 years 1 months ago
Metabolite coupling in genome-scale metabolic networks
Background: Biochemically detailed stoichiometric matrices have now been reconstructed for various bacteria, yeast, and for the human cardiac mitochondrion based on genomic and pr...
Scott A. Becker, Nathan D. Price, Bernhard O. Pals...
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EC
2006
195views ECommerce» more  EC 2006»
15 years 1 months ago
Automated Global Structure Extraction for Effective Local Building Block Processing in XCS
Learning Classifier Systems (LCSs), such as the accuracy-based XCS, evolve distributed problem solutions represented by a population of rules. During evolution, features are speci...
Martin V. Butz, Martin Pelikan, Xavier Llorà...
ISCI
2008
159views more  ISCI 2008»
15 years 1 months ago
Large scale evolutionary optimization using cooperative coevolution
Evolutionary algorithms (EAs) have been applied with success to many numerical and combinatorial optimization problems in recent years. However, they often lose their effectivenes...
Zhenyu Yang, Ke Tang, Xin Yao