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108
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BMCBI
2010
15 years 18 hour ago
2010
Background: Because a priori knowledge about function of G protein-coupled receptors (GPCRs) can provide useful information to pharmaceutical research, the determination of their ...
105
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BMCBI
2008
15 years 16 hour ago
2008
Background: As in many different areas of science and technology, most important problems in bioinformatics rely on the proper development and assessment of binary classifiers. A ...
92
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BMCBI
2010
15 years 16 hour ago
2010
Background: Nonnegative Matrix Factorization (NMF) is an unsupervised learning technique that has been applied successfully in several fields, including signal processing, face re...
113
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BMCBI
2010
15 years 16 hour ago
2010
Background: The goal of class prediction studies is to develop rules to accurately predict the class membership of new samples. The rules are derived using the values of the varia...
BMCBI
2010
15 years 16 hour ago
2010
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...