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BMCBI
2007
109views more  BMCBI 2007»
15 years 4 months ago
TABASCO: A single molecule, base-pair resolved gene expression simulator
Background: Experimental studies of gene expression have identified some of the individual molecular components and elementary reactions that comprise and control cellular behavio...
Sriram Kosuri, Jason R. Kelly, Drew Endy
BMCBI
2010
208views more  BMCBI 2010»
15 years 4 months ago
Calculation of accurate small angle X-ray scattering curves from coarse-grained protein models
Background: Genome sequencing projects have expanded the gap between the amount of known protein sequences and structures. The limitations of current high resolution structure det...
Kasper Stovgaard, Christian Andreetta, Jesper Ferk...
165
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CONSTRAINTS
2010
126views more  CONSTRAINTS 2010»
15 years 4 months ago
Lexicographically-ordered constraint satisfaction problems
Abstract. We describe a simple CSP formalism for handling multi-attribute preference problems with hard constraints, one that combines hard constraints and preferences so the two a...
Eugene C. Freuder, Robert Heffernan, Richard J. Wa...
CSCW
2008
ACM
15 years 4 months ago
Physical and Digital Artifact-Mediated Coordination in Building Design
We conducted an ethnographic field study examining how a building design team used representational artifacts to coordinate the design of building systems, structure, and architect...
Melanie Tory, Sheryl Staub-French, Barry A. Po, Fu...
ALMOB
2006
155views more  ALMOB 2006»
15 years 4 months ago
Refining motifs by improving information content scores using neighborhood profile search
The main goal of the motif finding problem is to detect novel, over-represented unknown signals in a set of sequences (e.g. transcription factor binding sites in a genome). The mo...
Chandan K. Reddy, Yao-Chung Weng, Hsiao-Dong Chian...