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» Functional site prediction selects correct protein models
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BMCBI
2010
131views more  BMCBI 2010»
14 years 9 months ago
A two-step site and mRNA-level model for predicting microRNA targets
Background: Despite experiments showing that the number of microRNA (miRNA) target sites is critical for miRNA targeting, most existing methods focus on identifying individual miR...
Takaya Saito, Pål Sætrom
BMCBI
2008
114views more  BMCBI 2008»
14 years 12 months ago
WSPMaker: a web tool for calculating selection pressure in proteins and domains using window-sliding
Background: In the study of adaptive evolution, it is important to detect the protein coding sites where natural selection is acting. In general, the ratio of the rate of non-syno...
Yong Seok Lee, Tae-Hyung Kim, Tae-Wook Kang, Won-H...
BMCBI
2010
191views more  BMCBI 2010»
14 years 6 months ago
Molecular dynamics simulation studies and in vitro site directed mutagenesis of avian beta-defensin Apl_AvBD2
Background: Defensins comprise a group of antimicrobial peptides, widely recognized as important elements of the innate immune system in both animals and plants. Cationicity, rath...
Soja Saghar Soman, Krishnankutty Chandrika Sivakum...
BMCBI
2005
117views more  BMCBI 2005»
14 years 11 months ago
An SVM-based system for predicting protein subnuclear localizations
Background: The large gap between the number of protein sequences in databases and the number of functionally characterized proteins calls for the development of a fast computatio...
Zhengdeng Lei, Yang Dai
ICAI
2007
15 years 1 months ago
A Graphical Game Model of Drug Binding
Abstract Drug-protein binding is the reversible interaction of drugs with proteins in an organism and is vital in helping the body reject invading pathogenic organisms. Predicting ...
Christina Boucher, Maja Omanovic