We present a novel classification-based algorithm called GeneClass for learning to predict gene regulatory response. Our approach is motivated by the hypothesis that in simple orga...
Manuel Middendorf, Anshul Kundaje, Chris Wiggins, ...
Background: We have recently introduced a predictive framework for studying gene transcriptional regulation in simpler organisms using a novel supervised learning algorithm called...
Anshul Kundaje, Manuel Middendorf, Mihir Shah, Chr...
Finding the location of binding sites in DNA is a difficult problem. Although the location of some binding sites have been experimentally identified, other parts of the genome may ...
Faisal Rezwan, Yi Sun, Neil Davey, Rod Adams, Alis...
Background: Predictive classification on the base of gene expression profiles appeared recently as an attractive strategy for identifying the biological functions of genes. Gene O...
Background: Genes work coordinately as gene modules or gene networks. Various computational approaches have been proposed to find gene modules based on gene expression data; for e...
Ting Gong, Jianhua Xuan, Li Chen, Rebecca B. Riggi...