Abstract. Protein function prediction represents a fundamental challenge in bioinformatics. The increasing availability of proteomics network data has enabled the development of se...
Similarity search in sequence databases is of paramount importance in bioinformatics research. As the size of the genomic databases increases, similarity search of proteins in the...
1 Profile Hidden Markov Models (profile HMMs) are used as a popular bioinformatics tool for sensitive database searching, e.g. a set of not annotated protein sequences is compared...
Microarray technology produces large amounts of information to be manipulated by analysis methods, such as biclustering algorithms, to extract new knowledge. All-purpose multivaria...
It is important in bioinformatics research and applications to select or discover informative genes of a tumor from microarray data. However, most of the existing methods are based...