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» HYPE Applied to the Modelling of Hybrid Biological Systems
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BMCBI
2010
208views more  BMCBI 2010»
14 years 12 months ago
A multi-filter enhanced genetic ensemble system for gene selection and sample classification of microarray data
Background: Feature selection techniques are critical to the analysis of high dimensional datasets. This is especially true in gene selection from microarray data which are common...
Pengyi Yang, Bing Bing Zhou, Zili Zhang, Albert Y....
BIOCOMP
2010
14 years 9 months ago
A Model Reduction Technique for Stochastic Biochemical Kinetics
Abstract-- Modeling the intermolecular reactions in a single cell is a critical problem in computational biology. Biochemical reaction systems often involve species in both low and...
Silvana Ilie, Ekaterina Kudashkina
BMCBI
2004
323views more  BMCBI 2004»
14 years 11 months ago
Biochemical Network Stochastic Simulator (BioNetS): software for stochastic modeling of biochemical networks
Background: Intrinsic fluctuations due to the stochastic nature of biochemical reactions can have large effects on the response of biochemical networks. This is particularly true ...
David Adalsteinsson, David McMillen, Timothy C. El...
BMCBI
2010
172views more  BMCBI 2010»
14 years 12 months ago
Comparison of evolutionary algorithms in gene regulatory network model inference
Background: The evolution of high throughput technologies that measure gene expression levels has created a data base for inferring GRNs (a process also known as reverse engineeri...
Alina Sîrbu, Heather J. Ruskin, Martin Crane
BIOINFORMATICS
2007
195views more  BIOINFORMATICS 2007»
14 years 12 months ago
Context-dependent clustering for dynamic cellular state modeling of microarray gene expression
Motivation: High-throughput expression profiling allows researchers to study gene activities globally. Genes with similar expression profiles are likely to encode proteins that ma...
Shinsheng Yuan, Ker-Chau Li