Sciweavers

176 search results - page 28 / 36
» Hidden conformations in protein structures
Sort
View
BMCBI
2007
141views more  BMCBI 2007»
14 years 10 months ago
Using structural motif descriptors for sequence-based binding site prediction
Background: Many protein sequences are still poorly annotated. Functional characterization of a protein is often improved by the identification of its interaction partners. Here, ...
Andreas Henschel, Christof Winter, Wan Kyu Kim, Mi...
JCC
2002
80views more  JCC 2002»
14 years 10 months ago
Consistent treatment of inter- and intramolecular polarization in molecular mechanics calculations
: A protocol is described for the treatment of molecular polarization in force field calculations. The resulting model is consistent in that both inter- and intramolecular polariza...
Pengyu Ren, Jay W. Ponder
BMCBI
2008
116views more  BMCBI 2008»
14 years 11 months ago
IgTM: An algorithm to predict transmembrane domains and topology in proteins
Background: Due to their role of receptors or transporters, membrane proteins play a key role in many important biological functions. In our work we used Grammatical Inference (GI...
Piedachu Peris, Damián López, Marcel...
NAR
2006
119views more  NAR 2006»
14 years 10 months ago
HHsenser: exhaustive transitive profile search using HMM-HMM comparison
HHsenser is the first server to offer exhaustive intermediate profile searches, which it combines with pairwise comparison of hidden Markov models. Starting from a single protein ...
Johannes Söding, Michael Remmert, Andreas Bie...
BMCBI
2008
103views more  BMCBI 2008»
14 years 11 months ago
Parameter estimation for robust HMM analysis of ChIP-chip data
Background: Tiling arrays are an important tool for the study of transcriptional activity, proteinDNA interactions and chromatin structure on a genome-wide scale at high resolutio...
Peter Humburg, David Bulger, Glenn Stone