Affymetrix microarrays have become a standard experimental platform for studies of mRNA expression profiling. Their success is due, in part, to the multiple oligonucleotide featur...
Background: A transcriptional regulatory module (TRM) is a set of genes that is regulated by a common set of transcription factors (TFs). By organizing the genome into TRMs, a liv...
s the development of an abstract description of what there is in the world in an application-independent form. This paper argues that attempts to support information systems intero...
Background: ChIP-chip data, which indicate binding of transcription factors (TFs) to DNA regions in vivo, are widely used to reconstruct transcriptional regulatory networks. Howev...
on abstract principles that you can't easily apply in a formal, deductive fashion. So, the favorite tools of logicians and mathematicians, such as firstorder logic, aren'...