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BMCBI
2006
108views more  BMCBI 2006»
15 years 3 months ago
Probe set algorithms: is there a rational best bet?
Affymetrix microarrays have become a standard experimental platform for studies of mRNA expression profiling. Their success is due, in part, to the multiple oligonucleotide featur...
Jinwook Seo, Eric P. Hoffman
BMCBI
2006
122views more  BMCBI 2006»
15 years 3 months ago
Computational reconstruction of transcriptional regulatory modules of the yeast cell cycle
Background: A transcriptional regulatory module (TRM) is a set of genes that is regulated by a common set of transcription factors (TFs). By organizing the genome into TRMs, a liv...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
CJ
2006
117views more  CJ 2006»
15 years 3 months ago
Atomic Hypermedia
s the development of an abstract description of what there is in the world in an application-independent form. This paper argues that attempts to support information systems intero...
Duncan Martin, Helen Ashman
BMCBI
2007
182views more  BMCBI 2007»
15 years 3 months ago
Identifying regulatory targets of cell cycle transcription factors using gene expression and ChIP-chip data
Background: ChIP-chip data, which indicate binding of transcription factors (TFs) to DNA regions in vivo, are widely used to reconstruct transcriptional regulatory networks. Howev...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
EXPERT
2006
156views more  EXPERT 2006»
15 years 3 months ago
Computational Models of Ethical Reasoning: Challenges, Initial Steps, and Future Directions
on abstract principles that you can't easily apply in a formal, deductive fashion. So, the favorite tools of logicians and mathematicians, such as firstorder logic, aren'...
Bruce M. McLaren
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