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BMCBI
2007
109views more  BMCBI 2007»
14 years 9 months ago
TABASCO: A single molecule, base-pair resolved gene expression simulator
Background: Experimental studies of gene expression have identified some of the individual molecular components and elementary reactions that comprise and control cellular behavio...
Sriram Kosuri, Jason R. Kelly, Drew Endy
BMCBI
2006
100views more  BMCBI 2006»
14 years 9 months ago
Using the nucleotide substitution rate matrix to detect horizontal gene transfer
Background: Horizontal gene transfer (HGT) has allowed bacteria to evolve many new capabilities. Because transferred genes perform many medically important functions, such as conf...
Micah Hamady, M. D. Betterton, Rob Knight
BMCBI
2004
135views more  BMCBI 2004»
14 years 9 months ago
Information assessment on predicting protein-protein interactions
Background: Identifying protein-protein interactions is fundamental for understanding the molecular machinery of the cell. Proteome-wide studies of protein-protein interactions ar...
Nan Lin, Baolin Wu, Ronald Jansen, Mark Gerstein, ...
BMCBI
2006
137views more  BMCBI 2006»
14 years 9 months ago
Chaos game representation for comparison of whole genomes
Background: Chaos game representation of genome sequences has been used for visual representation of genome sequence patterns as well as alignment-free comparisons of sequences ba...
Jijoy Joseph, Roschen Sasikumar
NAR
2010
143views more  NAR 2010»
14 years 4 months ago
WormBase: a comprehensive resource for nematode research
WormBase (http://www.wormbase.org) is a central data repository for nematode biology. Initially created as a service to the Caenorhabditis elegans research field, WormBase has evo...
Todd W. Harris, Igor Antoshechkin, Tamberlyn Bieri...