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BMCBI
2007
86views more  BMCBI 2007»
14 years 9 months ago
Toxicogenomic analysis incorporating operon-transcriptional coupling and toxicant concentration-expression response: analysis of
Background: Deficiencies in microarray technology cause unwanted variation in the hybridization signal, obscuring the true measurements of intracellular transcript levels. Here we...
William O. Ward, Carol D. Swartz, Steffen Porwolli...
BMCBI
2006
112views more  BMCBI 2006»
14 years 9 months ago
Argument-predicate distance as a filter for enhancing precision in extracting predications on the genetic etiology of disease
Background: Genomic functional information is valuable for biomedical research. However, such information frequently needs to be extracted from the scientific literature and struc...
Marco Masseroli, Halil Kilicoglu, François-...
NAR
2011
227views Computer Vision» more  NAR 2011»
14 years 4 months ago
VnD: a structure-centric database of disease-related SNPs and drugs
Numerous genetic variations have been found to be related to human diseases. Significant portion of those affect the drug response as well by changing the protein structure and fu...
Jin Ok Yang, Sangho Oh, Gunhwan Ko, Seong-Jin Park...
RECOMB
2002
Springer
15 years 10 months ago
Phase-independent rhythmic analysis of genome-wide expression patterns
We introduce a model-based analysis technique for extracting and characterizing rhythmic expression pro les from genome-wide DNA microarray hybridization data. These patterns are ...
Christopher James Langmead, Anthony K. Yan, C. Rob...
BMCBI
2010
157views more  BMCBI 2010»
14 years 9 months ago
SeqTrim: a high-throughput pipeline for pre-processing any type of sequence read
Background: High-throughput automated sequencing has enabled an exponential growth rate of sequencing data. This requires increasing sequence quality and reliability in order to a...
Juan Falgueras, Antonio J. Lara, Noé Fern&a...