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BCB
2010
127views Bioinformatics» more  BCB 2010»
14 years 7 months ago
A novel network model for molecular prognosis
Network-based genome-wide association studies (NWAS) utilize the molecular interactions between genes and functional pathways in biomarker identification. This study presents a no...
Ying-Wooi Wan, Swetha Bose, James Denvir, Nancy La...
BMCBI
2005
223views more  BMCBI 2005»
15 years 4 days ago
Bioinformatics approaches for cross-species liver cancer analysis based on microarray gene expression profiling
Background: The completion of the sequencing of human, mouse and rat genomes and knowledge of cross-species gene homologies enables studies of differential gene expression in anim...
Hong Fang, Weida Tong, Roger Perkins, Leming M. Sh...
BMCBI
2011
14 years 6 months ago
The PathOlogist: An Automated Tool for Pathway-Centric Analysis
Background: The PathOlogist is a new tool designed to transform large sets of gene expression data into quantitative descriptors of pathway-level behavior. The tool aims to provid...
Sharon I. Greenblum, Sol Efroni, Carl F. Schaefer,...
CSB
2005
IEEE
124views Bioinformatics» more  CSB 2005»
15 years 5 months ago
Identifying Local Gene Expression Patterns in Biomolecular Networks
This study is aimed at elucidating putative transcription regulators (TRs) responsible for the observed differential expression pattern. Combined direct promoter binding and indir...
Andrey Y. Sivachenko, Anton Yuryev, Nikolai Darase...
BMCBI
2006
82views more  BMCBI 2006»
15 years 9 days ago
Transcriptomic response to differentiation induction
Background: Microarrays used for gene expression studies yield large amounts of data. The processing of such data typically leads to lists of differentially-regulated genes. A com...
G. W. Patton, Robert M. Stephens, I. A. Sidorov, X...