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BMCBI
2002
101views more  BMCBI 2002»
14 years 9 months ago
Total sequence decomposition distinguishes functional modules, "molegos" in apurinic/apyrimidinic endonucleases
Background: Total sequence decomposition, using the web-based MASIA tool, identifies areas of conservation in aligned protein sequences. By structurally annotating these motifs, t...
Catherine H. Schein, Numan Özgün, Tadahi...
66
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RECOMB
1999
Springer
15 years 2 months ago
Classifying proteins by family using the product of correlated p-values
An important goal in bioinformatics is determining the homology and function of proteins from their sequences. Pairwise sequence similarity algorithms are often employed for this ...
Timothy L. Bailey, William Noble Grundy
BMCBI
2008
244views more  BMCBI 2008»
14 years 9 months ago
RNAalifold: improved consensus structure prediction for RNA alignments
Background: The prediction of a consensus structure for a set of related RNAs is an important first step for subsequent analyses. RNAalifold, which computes the minimum energy str...
Stephan H. F. Bernhart, Ivo L. Hofacker, Sebastian...
BMCBI
2005
119views more  BMCBI 2005»
14 years 9 months ago
The distance-profile representation and its application to detection of distantly related protein families
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
Chin-Jen Ku, Golan Yona
IPPS
2006
IEEE
15 years 3 months ago
Parallel implementation and performance characterization of MUSCLE
Multiple sequence alignment is a fundamental and very computationally intensive task in molecular biology. MUSCLE, a new algorithm for creating multiple alignments of protein sequ...
Xi Deng, Eric Li, Jiulong Shan, Wenguang Chen