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PKDD
2004
Springer
113views Data Mining» more  PKDD 2004»
15 years 2 months ago
Discovery of Regulatory Connections in Microarray Data
Abstract. In this paper, we introduce a new approach for mining regulatory interactions between genes in microarray time series studies. A number of preprocessing steps transform t...
Michael Egmont-Petersen, Wim de Jonge, Arno Siebes
PSB
2004
14 years 10 months ago
Modeling Cellular Processes with Variational Bayesian Cooperative Vector Quantizer
Gene expression of a cell is controlled by sophisticated cellular processes. The capability of inferring the states of these cellular processes would provide insight into the mech...
Xinghua Lu, Milos Hauskrecht, Roger S. Day
BMCBI
2008
135views more  BMCBI 2008»
14 years 9 months ago
Knowledge-guided multi-scale independent component analysis for biomarker identification
Background: Many statistical methods have been proposed to identify disease biomarkers from gene expression profiles. However, from gene expression profile data alone, statistical...
Li Chen, Jianhua Xuan, Chen Wang, Ie-Ming Shih, Yu...
JMLR
2010
159views more  JMLR 2010»
14 years 4 months ago
Inference of Sparse Networks with Unobserved Variables. Application to Gene Regulatory Networks
Networks are becoming a unifying framework for modeling complex systems and network inference problems are frequently encountered in many fields. Here, I develop and apply a gener...
Nikolai Slavov
BMCBI
2007
114views more  BMCBI 2007»
14 years 9 months ago
Large scale statistical inference of signaling pathways from RNAi and microarray data
Background: The advent of RNA interference techniques enables the selective silencing of biologically interesting genes in an efficient way. In combination with DNA microarray tec...
Holger Fröhlich, Mark Fellmann, Holger Sü...