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BMCBI
2006
202views more  BMCBI 2006»
14 years 10 months ago
Integrated biclustering of heterogeneous genome-wide datasets for the inference of global regulatory networks
Background: The learning of global genetic regulatory networks from expression data is a severely under-constrained problem that is aided by reducing the dimensionality of the sea...
David J. Reiss, Nitin S. Baliga, Richard Bonneau
DSS
2007
127views more  DSS 2007»
14 years 9 months ago
Large-scale regulatory network analysis from microarray data: modified Bayesian network learning and association rule mining
We present two algorithms for learning large-scale gene regulatory networks from microarray data: a modified informationtheory-based Bayesian network algorithm and a modified asso...
Zan Huang, Jiexun Li, Hua Su, George S. Watts, Hsi...
BMCBI
2008
166views more  BMCBI 2008»
14 years 10 months ago
Learning transcriptional regulatory networks from high throughput gene expression data using continuous three-way mutual informa
Background: Probability based statistical learning methods such as mutual information and Bayesian networks have emerged as a major category of tools for reverse engineering mecha...
Weijun Luo, Kurt D. Hankenson, Peter J. Woolf
BMCBI
2007
130views more  BMCBI 2007»
14 years 10 months ago
A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression da
Background: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, th...
Reuben Thomas, Carlos J. Paredes, Sanjay Mehrotra,...
BIRD
2008
Springer
141views Bioinformatics» more  BIRD 2008»
14 years 12 months ago
Nested q-Partial Graphs for Genetic Network Inference from "Small n, Large p" Microarray Data
Abstract. Gaussian graphical models are widely used to tackle the important and challenging problem of inferring genetic regulatory networks from expression data. These models have...
Kevin Kontos, Gianluca Bontempi