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TCBB
2008
137views more  TCBB 2008»
14 years 9 months ago
Toward Verified Biological Models
The last several decades have witnessed a vast accumulation of biological data and data analysis. Many of these data sets represent only a small fraction of the system's behav...
Avital Sadot, Jasmin Fisher, Dan Barak, Yishai Adm...
BIOINFORMATICS
2005
93views more  BIOINFORMATICS 2005»
14 years 9 months ago
Donuts, scratches and blanks: robust model-based segmentation of microarray images
Inner holes, artifacts and blank spots are common in microarray images, but current image analysis methods do not pay them enough attention. We propose a new robust model-based me...
Qunhua Li, Chris Fraley, Roger Eugene Bumgarner, K...
BMCBI
2005
114views more  BMCBI 2005»
14 years 9 months ago
Signal transduction pathway profiling of individual tumor samples
Background: Signal transduction pathways convey information from the outside of the cell to transcription factors, which in turn regulate gene expression. Our objective is to anal...
Thomas Breslin, Morten Krogh, Carsten Peterson, Ca...
BMCBI
2005
153views more  BMCBI 2005»
14 years 9 months ago
A comparative review of estimates of the proportion unchanged genes and the false discovery rate
Background: In the analysis of microarray data one generally produces a vector of p-values that for each gene give the likelihood of obtaining equally strong evidence of change by...
Per Broberg
BMCBI
2005
141views more  BMCBI 2005»
14 years 9 months ago
Construction and validation of the APOCHIP, a spotted oligo-microarray for the study of beta-cell apoptosis
Background: Type 1 diabetes mellitus (T1DM) is a autoimmune disease caused by a long-term negative balance between immune-mediated beta-cell damage and beta-cell repair/regenerati...
Nils E. Magnusson, Alessandra K. Cardozo, Mogens K...
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