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81
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BMCBI
2008
93views more  BMCBI 2008»
14 years 11 months ago
Homology modelling of protein-protein complexes: a simple method and its possibilities and limitations
Background: Structure-based computational methods are needed to help identify and characterize protein-protein complexes and their function. For individual proteins, the most succ...
Guillaume Launay, Thomas Simonson
92
Voted
BMCBI
2008
136views more  BMCBI 2008»
14 years 11 months ago
An efficient method for the prediction of deleterious multiple-point mutations in the secondary structure of RNAs using suboptim
Background: RNAmute is an interactive Java application which, given an RNA sequence, calculates the secondary structure of all single point mutations and organizes them into categ...
Alexander Churkin, Danny Barash
BMCBI
2008
111views more  BMCBI 2008»
14 years 11 months ago
Molecular docking studies of dithionitrobenzoic acid and its related compounds to protein disulfide isomerase: computational scr
Background: Entry of HIV-1 into human lymphoid requires activities of viral envelope glycoproteins gp120 and gp41, and two host-cell proteins, the primary receptor CD4 and a chemo...
Uthaman Gowthaman, Mannu Jayakanthan, Durai Sundar
CGF
2010
146views more  CGF 2010»
14 years 11 months ago
Pathline: A Tool For Comparative Functional Genomics
Biologists pioneering the new field of comparative functional genomics attempt to infer the mechanisms of gene regulation by looking for similarities and differences of gene activ...
Miriah D. Meyer, Bang Wong, Mark P. Styczynski, Ta...
94
Voted
AIM
2006
14 years 11 months ago
Comparative Analysis of Frameworks for Knowledge-Intensive Intelligent Agents
maintain awareness of its environment for a long period of time. Additionally, knowledge-intensive agents must be engineered such that their knowledge can be easily updated as envi...
Randolph M. Jones, Robert E. Wray III