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127
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BMCBI
2006
15 years 3 months ago
2006
Background: Biochemically detailed stoichiometric matrices have now been reconstructed for various bacteria, yeast, and for the human cardiac mitochondrion based on genomic and pr...
145
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BMCBI
2006
15 years 3 months ago
2006
Background: Expression microarray analysis is one of the most popular molecular diagnostic techniques in the post-genomic era. However, this technique faces the fundamental proble...
127
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BMCBI
2006
15 years 3 months ago
2006
Background:Receptors and scaffold proteins possess a number of distinct domains and bind multiple partners. A common problem in modeling signaling systems arises from a combinator...
138
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BMCBI
2006
15 years 3 months ago
2006
Background: Through the use of DNA microarrays it is now possible to obtain quantitative measurements of the expression of thousands of genes from a biological sample. This techno...
141
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BMCBI
2006
15 years 3 months ago
2006
Background: Many vital biological processes, including transcription and splicing, require a combination of short, degenerate sequence patterns, or motifs, adjacent to defined seq...