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NAR
2007
65views more  NAR 2007»
14 years 9 months ago
STRING 7 - recent developments in the integration and prediction of protein interactions
Information on protein–protein interactions is still mostly limited to a small number of model organisms, and originates from a wide variety of experimental and computational te...
Christian von Mering, Lars Juhl Jensen, Michael Ku...
BMCBI
2008
104views more  BMCBI 2008»
14 years 10 months ago
InteroPORC: an automated tool to predict highly conserved protein interaction networks
teps. First, we abstracted protein interactions onto orthologous cluster links. For a given source interaction, if both proteins belonged to a cluster, we constructed a link betwee...
Magali Michaut, Samuel Kerrien, Luisa Montecchi-Pa...
NAR
2011
257views Computer Vision» more  NAR 2011»
14 years 24 days ago
The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored
An essential prerequisite for any systems-level understanding of cellular functions is to correctly uncover and annotate all functional interactions among proteins in the cell. To...
Damian Szklarczyk, Andrea Franceschini, Michael Ku...
BMCBI
2010
83views more  BMCBI 2010»
14 years 10 months ago
Trees on networks: resolving statistical patterns of phylogenetic similarities among interacting proteins
Background: Phylogenies capture the evolutionary ancestry linking extant species. Correlations and similarities among a set of species are mediated by and need to be understood in...
William P. Kelly, Michael P. H. Stumpf
BIBE
2007
IEEE
142views Bioinformatics» more  BIBE 2007»
15 years 4 months ago
An HV-SVM Classifier to Infer TF-TF Interactions Using Protein Domains and GO Annotations
—Interactions between transcription factors (TFs) are necessary for deciphering the complex mechanisms of transcription regulation in eukaryotes. In this paper, we proposed a nov...
Xiaoli Li, Jun-Xiang Lee, Bharadwaj Veeravalli, Se...