Information on protein–protein interactions is still mostly limited to a small number of model organisms, and originates from a wide variety of experimental and computational te...
Christian von Mering, Lars Juhl Jensen, Michael Ku...
teps. First, we abstracted protein interactions onto orthologous cluster links. For a given source interaction, if both proteins belonged to a cluster, we constructed a link betwee...
Magali Michaut, Samuel Kerrien, Luisa Montecchi-Pa...
An essential prerequisite for any systems-level understanding of cellular functions is to correctly uncover and annotate all functional interactions among proteins in the cell. To...
Damian Szklarczyk, Andrea Franceschini, Michael Ku...
Background: Phylogenies capture the evolutionary ancestry linking extant species. Correlations and similarities among a set of species are mediated by and need to be understood in...
—Interactions between transcription factors (TFs) are necessary for deciphering the complex mechanisms of transcription regulation in eukaryotes. In this paper, we proposed a nov...