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157
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BMCBI
2010
154views more  BMCBI 2010»
15 years 1 months ago
Knowledge-based matrix factorization temporally resolves the cellular responses to IL-6 stimulation
Background: External stimulations of cells by hormones, cytokines or growth factors activate signal transduction pathways that subsequently induce a re-arrangement of cellular gen...
Andreas Kowarsch, Florian Blöchl, Sebastian B...
145
Voted
ACMSE
2006
ACM
15 years 10 months ago
Automatic quality assessment of Affymetrix GeneChip data
Computing reliable gene expression levels from microarray experiments is a sophisticated process with many potential pitfalls. Quality control is one of the most important steps i...
Steffen Heber, Beate Sick
JCB
2002
160views more  JCB 2002»
15 years 3 months ago
Inference from Clustering with Application to Gene-Expression Microarrays
There are many algorithms to cluster sample data points based on nearness or a similarity measure. Often the implication is that points in different clusters come from different u...
Edward R. Dougherty, Junior Barrera, Marcel Brun, ...
BMCBI
2004
108views more  BMCBI 2004»
15 years 3 months ago
Improving the scaling normalization for high-density oligonucleotide GeneChip expression microarrays
Background: Normalization is an important step for microarray data analysis to minimize biological and technical variations. Choosing a suitable approach can be critical. The defa...
Chao Lu
EVOW
2008
Springer
15 years 5 months ago
Detection of Quantitative Trait Associated Genes Using Cluster Analysis
Abstract. Many efforts have been involved in association study of quantitative phenotypes and expressed genes. The key issue is how to efficiently identify phenotype-associated gen...
Zhenyu Jia, Sha Tang, Dan Mercola, Shizhong Xu