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» Large scale hierarchical clustering of protein sequences
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BMCBI
2006
111views more  BMCBI 2006»
15 years 1 months ago
High throughput profile-profile based fold recognition for the entire human proteome
Background: In order to maintain the most comprehensive structural annotation databases we must carry out regular updates for each proteome using the latest profile-profile fold r...
Liam J. McGuffin, Richard T. Smith, Kevin Bryson, ...
BMCBI
2004
113views more  BMCBI 2004»
15 years 1 months ago
Influence of microarrays experiments missing values on the stability of gene groups by hierarchical clustering
Background: Microarray technologies produced large amount of data. The hierarchical clustering is commonly used to identify clusters of co-expressed genes. However, microarray dat...
Alexandre G. de Brevern, Serge A. Hazout, Alain Ma...
BMCBI
2007
116views more  BMCBI 2007»
15 years 1 months ago
Clustering protein environments for function prediction: finding PROSITE motifs in 3D
Background: Structural genomics initiatives are producing increasing numbers of threedimensional (3D) structures for which there is little functional information. Structure-based ...
Sungroh Yoon, Jessica C. Ebert, Eui-Young Chung, G...
BMCBI
2007
126views more  BMCBI 2007»
15 years 1 months ago
High-throughput identification of interacting protein-protein binding sites
Background: With the advent of increasing sequence and structural data, a number of methods have been proposed to locate putative protein binding sites from protein surfaces. Ther...
Jo-Lan Chung, Wei Wang, Philip E. Bourne
ALMOB
2006
109views more  ALMOB 2006»
15 years 1 months ago
A novel functional module detection algorithm for protein-protein interaction networks
Background: The sparse connectivity of protein-protein interaction data sets makes identification of functional modules challenging. The purpose of this study is to critically eva...
Woochang Hwang, Young-Rae Cho, Aidong Zhang, Mural...