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NAR
2007
91views more  NAR 2007»
14 years 9 months ago
RNABindR: a server for analyzing and predicting RNA-binding sites in proteins
Understanding interactions between proteins and RNA is key to deciphering the mechanisms of many important biological processes. Here we describe RNABindR, a web-based server that...
Michael Terribilini, Jeffry D. Sander, Jae-Hyung L...
BMCBI
2010
146views more  BMCBI 2010»
14 years 9 months ago
A pairwise residue contact area-based mean force potential for discrimination of native protein structure
Background: Considering energy function to detect a correct protein fold from incorrect ones is very important for protein structure prediction and protein folding. Knowledge-base...
Shahriar Arab, Mehdi Sadeghi, Changiz Eslahchi, Ha...
IHI
2012
291views Healthcare» more  IHI 2012»
13 years 5 months ago
PANI: an interactive data-driven tool for target prioritization in signaling networks
Biological network analysis often aims at the target identification problem, which is to predict which molecule to inhibit (or activate) for a disease treatment to achieve optimu...
Huey-Eng Chua, Sourav S. Bhowmick, Lisa Tucker-Kel...
BMCBI
2006
152views more  BMCBI 2006»
14 years 9 months ago
A two-stage approach for improved prediction of residue contact maps
Background: Protein topology representations such as residue contact maps are an important intermediate step towards ab initio prediction of protein structure. Although improvemen...
Alessandro Vullo, Ian Walsh, Gianluca Pollastri
BMCBI
2010
127views more  BMCBI 2010»
14 years 9 months ago
PeptideMine - A webserver for the design of peptides for protein-peptide binding studies derived from protein-protein interactom
Background: Signal transduction events often involve transient, yet specific, interactions between structurally conserved protein domains and polypeptide sequences in target prote...
Khader Shameer, Lalima L. Madan, Shivamurthy Veera...