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ALMOB
2006
80views more  ALMOB 2006»
14 years 12 months ago
Pattern statistics on Markov chains and sensitivity to parameter estimation
Background: In order to compute pattern statistics in computational biology a Markov model is commonly used to take into account the sequence composition. Usually its parameter mu...
Grégory Nuel
BMCBI
2006
118views more  BMCBI 2006»
14 years 12 months ago
Microarray image analysis: background estimation using quantile and morphological filters
Background: In a microarray experiment the difference in expression between genes on the same slide is up to 103 fold or more. At low expression, even a small error in the estimat...
Anders Bengtsson, Henrik Bengtsson
BMCBI
2006
143views more  BMCBI 2006»
14 years 12 months ago
IsoSVM - Distinguishing isoforms and paralogs on the protein level
Background: Recent progress in cDNA and EST sequencing is yielding a deluge of sequence data. Like database search results and proteome databases, this data gives rise to inferred...
Michael Spitzer, Stefan Lorkowski, Paul Cullen, Al...
BMCBI
2006
100views more  BMCBI 2006»
14 years 12 months ago
Towards a better solution to the shortest common supersequence problem: the deposition and reduction algorithm
Background: The problem of finding a Shortest Common Supersequence (SCS) of a set of sequences is an important problem with applications in many areas. It is a key problem in biol...
Kang Ning, Hon Wai Leong
BMCBI
2006
112views more  BMCBI 2006»
14 years 12 months ago
A correlated motif approach for finding short linear motifs from protein interaction networks
Background: An important class of interaction switches for biological circuits and disease pathways are short binding motifs. However, the biological experiments to find these bin...
Soon-Heng Tan, Hugo Willy, Wing-Kin Sung, See-Kion...