We introduce a model of DNA sequence evolution which can account for biases in mutation rates that depend on the identity of the neighboring bases. An analytic solution for this c...
Background: Through the use of DNA microarrays it is now possible to obtain quantitative measurements of the expression of thousands of genes from a biological sample. This techno...
Abstract. Hierarchical clustering is a popular method for grouping together similar elements based on a distance measure between them. In many cases, annotation information for som...
Saket Navlakha, James Robert White, Niranjan Nagar...
One of the major goals of computational sequence analysis is to find sequence similarities, which could serve as evidence of structural and functional conservation, as well as of ...
DNA sequence analysis depends on the accurate assembly of fragment reads for the determination of a consensus sequence. This report examines the possibility of analyzing multiple,...