Background: ChIP-chip data, which indicate binding of transcription factors (TFs) to DNA regions in vivo, are widely used to reconstruct transcriptional regulatory networks. Howev...
Motivation: Sigma factors regulate the expression of genes in Bacillus subtilis at the transcriptional level. First we assess the ability of currently available gene regulatory ne...
Michiel J. L. de Hoon, Yuko Makita, Seiya Imoto, K...
- Identification and annotation of all the functional elements in the genome, including genes and regulatory sequences, is a fundamental challenge in genomics and computational bio...
Mohammad Al Bataineh, Lun Huang, Ismaeel Muhamed, ...
We introduce a model-based analysis technique for extracting and characterizing rhythmic expression pro les from genome-wide DNA microarray hybridization data. These patterns are ...
Christopher James Langmead, Anthony K. Yan, C. Rob...
Abstract. We introduce an extended computational framework for studying biological systems. Our approach combines formalization of existing qualitative models that are in wide but ...
Irit Gat-Viks, Amos Tanay, Daniela Raijman, Ron Sh...