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BMCBI
2008
152views more  BMCBI 2008»
14 years 10 months ago
Predicting biological system objectives de novo from internal state measurements
Background: Optimization theory has been applied to complex biological systems to interrogate network properties and develop and refine metabolic engineering strategies. For examp...
Erwin P. Gianchandani, Matthew A. Oberhardt, Antho...
SGAI
2007
Springer
15 years 4 months ago
Learning Sets of Sub-Models for Spatio-Temporal Prediction
In this paper we describe a novel technique which implements a spatiotemporal model as a set of sub-models based on first order logic. These sub-models model different, typicall...
Andrew Bennett, Derek R. Magee
BMCBI
2008
129views more  BMCBI 2008»
14 years 10 months ago
An analytic and systematic framework for estimating metabolic flux ratios from 13C tracer experiments
Background: Metabolic fluxes provide invaluable insight on the integrated response of a cell to environmental stimuli or genetic modifications. Current computational methods for e...
Ari Rantanen, Juho Rousu, Paula Jouhten, Nicola Za...
ENGL
2007
89views more  ENGL 2007»
14 years 10 months ago
Similarity-based Heterogeneous Neural Networks
This research introduces a general class of functions serving as generalized neuron models to be used in artificial neural networks. They are cast in the common framework of comp...
Lluís A. Belanche Muñoz, Julio Jose ...
BMCBI
2006
101views more  BMCBI 2006»
14 years 10 months ago
SynTReN: a generator of synthetic gene expression data for design and analysis of structure learning algorithms
Background: The development of algorithms to infer the structure of gene regulatory networks based on expression data is an important subject in bioinformatics research. Validatio...
Tim Van den Bulcke, Koen Van Leemput, Bart Naudts,...