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BMCBI
2011
14 years 8 months ago
Clustering gene expression data with a penalized graph-based metric
Background: The search for cluster structure in microarray datasets is a base problem for the so-called “-omic sciences”. A difficult problem in clustering is how to handle da...
Ariel E. Bayá, Pablo M. Granitto
BMCBI
2011
14 years 8 months ago
Inference of Chromosome-Specific Copy Numbers Using Population Haplotypes
Background: Using microarray and sequencing platforms, a large number of copy number variations (CNVs) have been identified in humans. In practice, because our human genome is a d...
Yao-Ting Huang, Min-Han Wu
BMCBI
2011
14 years 8 months ago
Improving pan-genome annotation using whole genome multiple alignment
Background: Rapid annotation and comparisons of genomes from multiple isolates (pan-genomes) is becoming commonplace due to advances in sequencing technology. Genome annotations c...
Samuel V. Angiuoli, Julie C. Dunning Hotopp, Steve...
NAR
2011
214views Computer Vision» more  NAR 2011»
14 years 8 months ago
DAnCER: Disease-Annotated Chromatin Epigenetics Resource
Chromatin modification (CM) is a set of epigenetic processes that govern many aspects of DNA replication, transcription and repair. CM is carried out by groups of physically inter...
Andrei L. Turinsky, Brian Turner, Rosanne C. Borja...
NAR
2011
340views Computer Vision» more  NAR 2011»
14 years 8 months ago
CCDB: a curated database of genes involved in cervix cancer
The Cervical Cancer gene DataBase (CCDB, http:// crdd.osdd.net/raghava/ccdb) is a manually curated catalog of experimentally validated genes that are thought, or are known to be i...
Subhash M. Agarwal, Dhwani Raghav, Harinder Singh,...
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