721 search results - page 133 / 145 » Mining Information for Functional Genomics |
121
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BMCBI
2007
15 years 1 months ago
2007
Background: Three-color microarray experiments can be performed to assess drug effects on the genomic scale. The methodology may be useful in shortening the cycle, reducing the co...
108
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BMCBI
2008
15 years 1 months ago
2008
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
120
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BMCBI
2008
15 years 1 months ago
2008
Background: Most gene finders score candidate gene models with state-based methods, typically HMMs, by combining local properties (coding potential, splice donor and acceptor patt...
110
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BMCBI
2008
15 years 1 months ago
2008
Background: The expansion of raw protein sequence databases in the post genomic era and availability of fresh annotated sequences for major localizations particularly motivated us...
122
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ALMOB
2006
15 years 1 months ago
2006
Background: Automated software tools for multiple alignment often fail to produce biologically meaningful results. In such situations, expert knowledge can help to improve the qua...